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2005 2
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Ca(2+) binding to F-ATP synthase beta subunit triggers the mitochondrial permeability transition.
Giorgio V, Burchell V, Schiavone M, Bassot C, Minervini G, Petronilli V, Argenton F, Forte M, Tosatto S, Lippe G, Bernardi P. Giorgio V, et al. EMBO Rep. 2017 Jul;18(7):1065-1076. doi: 10.15252/embr.201643354. Epub 2017 May 15. EMBO Rep. 2017. PMID: 28507163 Free PMC article.
F-ATP synthases convert the electrochemical energy of the H(+) gradient into the chemical energy of ATP with remarkable efficiency. ...Through in vitro, in vivo and in silico studies we (i) pinpoint the "Ca(2+)-trigger site" of the PTP to the catalytic site o …
F-ATP synthases convert the electrochemical energy of the H(+) gradient into the chemical energy of ATP with remarkable …
Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation.
Ganetzky RD, Markhard AL, Yee I, Clever S, Cahill A, Shah H, Grabarek Z, To TL, Mootha VK. Ganetzky RD, et al. N Engl J Med. 2022 Oct 13;387(15):1395-1403. doi: 10.1056/NEJMoa2202949. N Engl J Med. 2022. PMID: 36239646 Free PMC article.
An evaluation of their fibroblasts showed elevated oxygen consumption and decreased mitochondrial membrane potential. Exome analysis revealed a de novo heterozygous variant in ATP5F1B, which encodes the beta subunit of mitochondrial ATP …
An evaluation of their fibroblasts showed elevated oxygen consumption and decreased mitochondrial membrane potential. Exome analysis …
ATP synthase beta-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus.
Li W, Li SJ, Yin TL, Yang J, Cheng Y. Li W, et al. J Huazhong Univ Sci Technolog Med Sci. 2017 Apr;37(2):210-216. doi: 10.1007/s11596-017-1717-9. Epub 2017 Apr 11. J Huazhong Univ Sci Technolog Med Sci. 2017. PMID: 28397049
This study investigated the abnormal expression of ATP synthase beta-subunit (ATPsyn-beta) in pancreas islets of rat model of polycystic ovary syndrome (PCOS) with type 2 diabetes mellitus (T2DM), and the secretion function changes after up-regu …
This study investigated the abnormal expression of ATP synthase beta-subunit (ATPsyn-beta) in pancreas is …
ATP Synthase Subunit Beta Immunostaining is Reduced in the Sclerotic Hippocampus of Epilepsy Patients.
Mota MVB, Zaidan BC, do Canto AM, Ghizoni E, Tedeschi H, de Souza Queiroz L, Alvim MKM, Cendes F, Lopes-Cendes I, Schenka AA, Vieira AS, Rogerio F. Mota MVB, et al. Cell Mol Neurobiol. 2019 Jan;39(1):149-160. doi: 10.1007/s10571-018-0641-2. Epub 2018 Dec 11. Cell Mol Neurobiol. 2019. PMID: 30539418
We have recently studied, by using mass spectrometry-based proteomics, an experimental model of TLE induced by electrical stimulation. Specifically, protein expressions of both the beta subunit of mitochondrial ATP synthase (ATP5B) and of …
We have recently studied, by using mass spectrometry-based proteomics, an experimental model of TLE induced by electrical stimulation. Speci …
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity.
Lu Y, Ma J, Song Z, Ye Y, Fu PP, Lin G. Lu Y, et al. Arch Toxicol. 2018 Nov;92(11):3403-3414. doi: 10.1007/s00204-018-2309-6. Epub 2018 Sep 22. Arch Toxicol. 2018. PMID: 30244272
The present study revealed that ATP synthase subunit beta (ATP5B), a critical subunit of mitochondrial ATP synthase, was a protein bound to the reactive pyrrolic metabolites forming pyrrole-ATP5B adduct. ...After trea …
The present study revealed that ATP synthase subunit beta (ATP5B), a critical subunit of mitochondrial …
Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase beta Subunit.
Tran L, Hanavan PD, Campbell LE, De Filippis E, Lake DF, Coletta DK, Roust LR, Mandarino LJ, Carroll CC, Katsanos CS. Tran L, et al. PLoS One. 2016 Aug 17;11(8):e0160057. doi: 10.1371/journal.pone.0160057. eCollection 2016. PLoS One. 2016. PMID: 27532680 Free PMC article.
Our previous studies show reduced abundance of the beta-subunit of mitochondrial H+-ATP synthase (beta-F1-ATPase) in skeletal muscle of obese individuals. The beta-F1-ATPase forms the catalytic core of the ATP synthase …
Our previous studies show reduced abundance of the beta-subunit of mitochondrial H+-ATP synthase (beta …
Human brain endothelial ATP synthase beta-subunit is mannose-insensitive binding target of FimH.
Shin S, Kim KS. Shin S, et al. FEMS Microbiol Lett. 2010 Feb;303(2):156-62. doi: 10.1111/j.1574-6968.2009.01878.x. Epub 2009 Dec 7. FEMS Microbiol Lett. 2010. PMID: 20067530 Free PMC article.
In this study, we showed that FimH also binds to HBMEC, independent of mannose, and identified ATP synthase beta-subunit and actin proteins from the surface biotinylated HBMEC as the mannose-insensitive binding targets for FimH. Co-immunoprecipitation …
In this study, we showed that FimH also binds to HBMEC, independent of mannose, and identified ATP synthase beta-sub …
A monoclonal antibody against F1-F0 ATP synthase beta subunit.
Yuan J, Zhang C, Fang S, Zhuang Z, Ling S, Wang S. Yuan J, et al. Hybridoma (Larchmt). 2012 Oct;31(5):352-7. doi: 10.1089/hyb.2012.0033. Hybridoma (Larchmt). 2012. PMID: 23098302
As a transmembrane enzyme, ATP synthase plays an important role in energy metabolism of organ tissues, as well as in tumors. ...Western blot assay revealed that the hybridoma clone reacted specifically with the ATP synthase beta subunit, …
As a transmembrane enzyme, ATP synthase plays an important role in energy metabolism of organ tissues, as well as in tumors. . …
Control of the ATP synthase beta subunit expression by RNA-binding proteins TIA-1, TIAR, and HuR.
Izquierdo JM. Izquierdo JM. Biochem Biophys Res Commun. 2006 Sep 22;348(2):703-11. doi: 10.1016/j.bbrc.2006.07.114. Epub 2006 Jul 28. Biochem Biophys Res Commun. 2006. PMID: 16890199
The beta-subunit of the mitochondrial H+-ATP synthase (beta-F1-ATPase) catalyzes the rate-limiting step of ATP formation in eukaryotic cells. ...Biochemical analysis revealed that the adenosine/uridine (AU)-rich element-bind …
The beta-subunit of the mitochondrial H+-ATP synthase (beta-F1-ATPase) catalyzes the rate-limiting …
Human ATP synthase beta is phosphorylated at multiple sites and shows abnormal phosphorylation at specific sites in insulin-resistant muscle.
Højlund K, Yi Z, Lefort N, Langlais P, Bowen B, Levin K, Beck-Nielsen H, Mandarino LJ. Højlund K, et al. Diabetologia. 2010 Mar;53(3):541-51. doi: 10.1007/s00125-009-1624-0. Epub 2009 Dec 12. Diabetologia. 2010. PMID: 20012595
The aim of this study was to identify and quantify site-specific phosphorylation of the catalytic beta subunit of ATP synthase (ATPsyn-beta) and determine protein abundance of ATPsyn-beta and other OxPhos components in skeletal mus …
The aim of this study was to identify and quantify site-specific phosphorylation of the catalytic beta subunit of ATP …
44 results